2006 Mercedes-Benz E-Class
The Verdict
Worst problem area
Fuel System
Fuel System leads by volume: 296 of 535 complaints (55%) mention it. Complaints mentioning Airbags & Restraints include more reported injuries (13) than those mentioning any other identified area.
Complaints filed rose from 527 in 2005 to 535 in 2006.
Data last changed . Sources: NHTSA complaints and recalls, EPA fuel economy data. Methodology
Cost, Fuel Economy & Complaint History
| Category | 2004 | 2005 | 2006 | 2007 | 2008 | vs. 2006 Midsize Cars |
|---|---|---|---|---|---|---|
| Annual fuel cost ($) | 3,900–5,150 | 3,300–5,150 | 3,300–5,150 | 3,450–5,550 | 3,450–5,550 | |
| Combined MPG | 15–20 | 15–27 | 15–27 | 14–26 | 14–26 | |
| City / Highway MPG | 13–17 / 19–24 | 13–23 / 18–33 | 13–23 / 18–33 | 12–23 / 18–32 | 12–23 / 18–32 | |
| CO₂ tailpipe (g/mi) | 444–592 | 377–592 | 377–592 | 392–635 | 392–635 | |
| Complaints filed | 481 | 527 | 535 | 433 | 219 | |
| Recalls issued | 7 | 6 | 5 | 5 | 4 | |
| Crash-involved complaints | 12 | 16 | 18 | 2 | 9 | |
| Fire-involved complaints | 3 | 4 | 9 | 10 | 9 | |
| Injuries reported | 8 | 19 | 22 | 12 | 11 | |
| Deaths reported | 0 | 4 | 1 | 0 | 0 | |
| Configurations compared | 5 | 6 | 6 | 6 | 6 |
Not compared: this database has no vehicle sales or registration figures, so a raw count mostly reflects how many were sold, not how safe the vehicle is.
Common questions
How many recalls does the 2006 Mercedes-Benz E-Class have?
5 NHTSA recall campaigns as of Sep 16, 2026. Check your VIN with NHTSA to see whether one applies to your car.
What is the most common complaint about the 2006 Mercedes-Benz E-Class?
Fuel System: 296 of 535 NHTSA complaints (55%) mention it.
What gas mileage does the 2006 Mercedes-Benz E-Class get?
EPA rates it 15–27 MPG combined.
How much does it cost to fuel a 2006 Mercedes-Benz E-Class?
EPA estimates $3,300–$5,150 a year in fuel costs, using EPA's assumptions.
Similar Vehicles
EPA-Rated Configurations (10)
| Configuration | Transmission | Cylinders | Displacement | Drivetrain | Fuel Type | Vehicle Class | City | Highway | Combined | Annual Fuel Cost | CO₂ |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Configuration 1 | Automatic 5-spd | 6 | 3.2L | Rear-Wheel Drive | Diesel | Midsize Cars | 23 mpg (high) | 33 mpg (high) | 27 mpg (high) | $3,300 (low) | 377 g/mi (low) |
| Configuration 2 | Automatic 7-spd | 6 | 3.5L | Rear-Wheel Drive | Premium | Midsize Cars | 17 mpg | 25 mpg | 20 mpg | $3,900 | 444 g/mi |
| Configuration 3 | Automatic 5-spd | 6 | 3.5L | 4-Wheel or All-Wheel Drive | Premium | Midsize Cars | 16 mpg | 23 mpg | 19 mpg | $4,100 | 468 g/mi |
| Configuration 4 | Automatic 7-spd | 8 | 5.0L | Rear-Wheel Drive | Premium | Midsize Cars | 15 mpg | 23 mpg | 18 mpg | $4,300 | 494 g/mi |
| Configuration 5 | Automatic 5-spd | 8 | 5.0L | 4-Wheel or All-Wheel Drive | Premium | Midsize Cars | 14 mpg | 19 mpg | 16 mpg | $4,850 | 555 g/mi |
| Configuration 6 | Automatic (S5) | 8 | 5.4L | Rear-Wheel Drive | Premium | Midsize Cars | 13 mpg (low) | 19 mpg | 16 mpg | $4,850 | 555 g/mi |
| Configuration 7 | Automatic 7-spd | 6 | 3.5L | Rear-Wheel Drive | Premium | Midsize Station Wagons | 16 mpg | 24 mpg | 19 mpg | $4,100 | 468 g/mi |
| Configuration 8 | Automatic 5-spd | 6 | 3.5L | 4-Wheel or All-Wheel Drive | Premium | Midsize Station Wagons | 16 mpg | 22 mpg | 18 mpg | $4,300 | 494 g/mi |
| Configuration 9 | Automatic 5-spd | 8 | 5.0L | 4-Wheel or All-Wheel Drive | Premium | Midsize Station Wagons | 14 mpg | 18 mpg (low) | 16 mpg | $4,850 | 555 g/mi |
| Configuration 10 | Automatic (S5) | 8 | 5.4L | Rear-Wheel Drive | Premium | Midsize Station Wagons | 13 mpg (low) | 20 mpg | 15 mpg (low) | $5,150 (high) | 592 g/mi (high) |
Complaints by Category
| Category | Complaints | Crash-Involved | Fire-Involved | Injuries | Deaths |
|---|---|---|---|---|---|
| Engine | 73 | 4 | 4 | 10 | 1 |
| Transmission & Drivetrain | 39 | 1 | 0 | 1 | 0 |
| Fuel System | 296 | 2 | 5 | 2 | 0 |
| Electrical | 24 | 0 | 1 | 0 | 0 |
| Brakes | 77 | 4 | 0 | 2 | 0 |
| Steering | 9 | 2 | 0 | 1 | 0 |
| Suspension, Wheels & Tires | 24 | 0 | 0 | 0 | 0 |
| Airbags & Restraints | 25 | 8 | 0 | 13 | 1 |
| Driver Assistance & Speed Control | 9 | 3 | 0 | 4 | 0 |
| Body, Seats & Latches | 9 | 1 | 0 | 8 | 1 |
| Visibility & Lighting | 20 | 0 | 1 | 0 | 0 |
| Other | 14 | 0 | 1 | 0 | 0 |
A complaint that names more than one category is counted in each, so the rows can add up to more than the total number of complaints.
Recalls (5)
VISIBILITY:SUN/MOON ROOF ASSEMBLY · Campaign 24V874000 · Nov 20, 2024
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please see the recall report for a complete list of models and model years. The glass sunroof panel may not be properly secured and can detach.
Consequence: A detached sunroof panel can become a road hazard, increasing the risk of a crash.
Remedy: Dealers will inspect and replace the sunroof panel as necessary, free of charge. Owner notification letters were mailed January 10, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of previous NHTSA recall number 22V-954. MBUSA's number for this recall is 2024120001/2/3.
VISIBILITY:SUN/MOON ROOF ASSEMBLY · Campaign 22V954000 · Dec 27, 2022
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The glass sunroof panel may not be properly secured and may detach.
Consequence: A detached sunroof panel may become a road hazard, increasing the risk of a crash.
Remedy: Dealers will inspect and replace the sunroof panel as necessary free of charge. Owner notification letters were mailed February 3, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands NHTSA recall number 19V-918. MBUSA's numbers for this recall are 2023010004, 2023010005, and 2023010006.
VISIBILITY:SUN/MOON ROOF ASSEMBLY · Campaign 21V196000 · Mar 22, 2021
Defect: Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2007 C350, C230, C280, CLK350, E320CDI, E350 Wagon, E350, 2006 C55 AMG, CLK500, CLS500, CLS55 AMG, E500 Wagon, E500, E55 AMG, 2007 CLK550, CLS550, CLS63 AMG, E550, E63 AMG, and E63 Wagon AMG vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly causing the glass panel to detach from the vehicle.
Consequence: A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.
Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. Owner letters were mailed May 7, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall number 19V-918. MBUSA's number for this recall is 2021040012.
VISIBILITY:SUN/MOON ROOF ASSEMBLY · Campaign 19V918000 · Dec 23, 2019
Defect: Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2001-2011 vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly resulting in the glass panel detaching from the vehicle. For a full list of the affected models visit: https://static.nhtsa.gov/odi/rcl/2019/RMISC-19V918-4126.pdf
Consequence: A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.
Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. The recall began July 10, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020040011.
ELECTRICAL SYSTEM · Campaign 08V303000 · Jul 9, 2008
Defect: MERCEDES-BENZ IS RECALLING MY 2006-2008 M-CLASS, R-CLASS, MY 2005-2009 SLK-CLASS, MY 2005-2008 C-CLASS, MY 2003-2004 AND 2006-2008 CLK-CLASS, MY 2003-2008 E-CLASS, MY 2004 AND 2008 CL-CLASS, MY 2008 CLS-CLASS, MY 2004 AND 2007-2008 S-CLASS, MY 2003 G-CLASS, AND MY 2003-2004, 2006 AND 2009 SL-CLASS VEHICLES. A SOFTWARE CALIBRATION NUMBER (SCN) CODING RECEIVED ON THE AFFECTED VEHICLES DURING A RECENT WORKSHOP VISIT WAS INCORRECT. DEPENDING ON THE MODEL YEAR AND MODEL AFFECTED, THE RESULTS OF AN INCORRECT SCN CODING CAN AFFECT A NUMBER OF VEHICLE SAFETY AND EMISSION FUNCTIONS INCLUDING THE FOLLOWING TYPES OF FUNCTIONS: (1) THE FUEL GAUGE READINGS MAY BE INCORRECT; (2) A STUCK FUEL-LEVEL SENSOR MAY NOT BE DISPLAYED IN THE INSTRUMENT CLUSTER; (3) THE OBD SYSTEM MAY CAUSE THE CHECK ENGINE LIGHT TO ILLUMINATE INCORRECTLY; AND, (4) THE SPEEDOMETER MAY BE OUT OF TOLERANCE.
Consequence: IN THE EVENT OF A VEHICLE CRASH, THE ELECTRICAL FUEL PUMP MAY NOT RECEIVE A CRASH SIGNAL THAT IS REQUIRED FOR THE FUEL PUMP TO DISCONNECT AND PREVENT FUTURE FUEL DELIVERY AS DESIGNED.
Remedy: DEALERS WILL RECODE THE SCN FREE OF CHARGE. THE RECALL BEGAN ON AUGUST 30, 2008. OWNERS MAY CONTACT MERCEDES-BENZ AT 1-800-367-6372.